Cat. Number:

Anti-RBM38抗體KL-7682R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a Anti-RBM38抗體cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Also known as:

SEB4D; CLL associated antigen KW 5; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding Anti-RBM38抗體motif protein 38; RNA binding protein 38; RNA binding region (RNP1, RRM) containing 1; RNA binding region containing protein 1; RNA-binding motif protein 38; RNA-binding protein 38; RNA-binding region-containing protein 1; RNPC1; SEB4; SEB4B; ssDNA binding protein SEB4; ssDNA-binding protein SEB4.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-RBM38抗體
Optimal working dilutions must be determined by the end user.