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產品詳情
  • 產品名稱:Anti-Phospho-P105 RB (Ser788)抗體

  • 產品型號:磷酸化視網膜母細胞瘤相關蛋白1抗體
  • 產品廠商:KALANG
  • 產品文檔:
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簡單介紹:
Anti-Phospho-P105 RB (Ser788)抗體產品質量穩定,實驗效果明顯,貨期快,價格優惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-P105 RB (Ser788)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit  Anti-Phospho-P105 RB (Ser788)
Cat. Number:
Anti-Phospho-P105 RB (Ser788)抗體KL-5665R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including Anti-Phospho-P105 RB (Ser788)抗體E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Also known as:
RB1(phospho S788); Rb(Phospho-Ser788); Anti-Phospho-P105 RB (Ser788)抗體p105-Rb (phospho-Ser788); p105-Rb (phospho Ser788); p-Rb (Ser788); OSRC; P105 RB; P105RB; PP105; PP110; pRb; RB 1; RB1; RB1 protein; Retinoblastoma 1 (including osteosarcoma); Retinoblastoma 1; Retinoblastoma associated protein; Retinoblastoma related osteosarcoma; Retinoblastoma susceptibility gene; Including osteosarcoma; RB_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Dog, Anti-Phospho-P105 RB (Ser788)抗體Pig, Cow, Horse, Rabbit, Sheep, .
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Ser788.
Predicted Molecular Weight: 102kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-Phospho-P105 RB (Ser788)抗體
Optimal working dilutions must be determined by the end user.

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