產品詳情
簡單介紹：
Anti-ARRB1/Beta-arrestin 1抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-ARRB1/Beta-arrestin 1抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-ARRB1/Beta-arrestin 1
Cat. Number:
Anti-ARRB1/Beta-arrestin 1抗體KL-20232R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling.Anti-ARRB1/Beta-arrestin 1抗體 It mediates agonist dependent desensitization and internalization of G protein coupled receptors (GPCRs, e.g., beta 2 adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to Anti-ARRB1/Beta-arrestin 1抗體activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Also known as:
Beta arrestin 1; ARB 1; ARB1; ARR 1; ARR1; ARRB 1; ARRB1; Arrestin beta 1; ARRB1_HUMAN; Arrestin 2; Arrestin beta-1; Beta-arrestin-1.Anti-ARRB1/Beta-arrestin 1抗體
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Beta-arrestin 1.
●
Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-ARRB1/Beta-arrestin 1抗體determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-ARRB1/Beta-arrestin 1抗體determined by the end user.
kl229Hu01 骨骼肌慢肌肌鈣蛋白I(TNNI1)多克隆抗體 Polyclonal Antibody to Troponin I Type 1, Slow Skeletal (TNNI1)
kl229Ra01 骨骼肌慢肌肌鈣蛋白I(TNNI1)多克隆抗體 Polyclonal Antibody to Troponin I Type 1, Slow Skeletal (TNNI1)
kl230Hu01 骨骼肌快肌肌鈣蛋白I(TNNI2)多克隆抗體 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl230Mu01 骨骼肌快肌肌鈣蛋白I(TNNI2)多克隆抗體 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl230Ra01 骨骼肌快肌肌鈣蛋白I(TNNI2)多克隆抗體 Polyclonal Antibody to Troponin I Type 2, Fast Skeletal (TNNI2)
kl231Hu01 骨骼肌慢肌肌鈣蛋白T(TNNT1)多克隆抗體 Polyclonal Antibody to Troponin T Type 1, Slow Skeletal (TNNT1)
kl232Hu01 心肌肌鈣蛋白T(TNNT2)多克隆抗體 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl232Mu01 心肌肌鈣蛋白T(TNNT2)多克隆抗體 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl232Ra01 心肌肌鈣蛋白T(TNNT2)多克隆抗體 Polyclonal Antibody to Troponin T Type 2, Cardiac (TNNT2)
kl234Hu01 角蛋白6A(KRT6A)多克隆抗體 Polyclonal Antibody to Keratin 6A (KRT6A)
kl236Hu01 白三烯A4水解酶(LTA4H)多克隆抗體 Polyclonal Antibody to Leukotriene A4 Hydrolase (LTA4H)
kl236Mu01 白三烯A4水解酶(LTA4H)多克隆抗體 Polyclonal Antibody to Leukotriene A4 Hydrolase (LTA4H)
kl252Hu01 饑餓素/肥胖抑制素前**原(GHRL)多克隆抗體 Polyclonal Antibody to Ghrelin/Obestatin Preprohormone (GHRL)
kl263Hu01 細胞周期素A1(CCNA1)多克隆抗體 Polyclonal Antibody to Cyclin A1 (CCNA1)
kl264Hu01 細胞周期素B(CCNB)多克隆抗體 Polyclonal Antibody to Cyclin B (CCNB)
kl265Hu01 細胞周期素B2(CCNB2)多克隆抗體 Polyclonal Antibody to Cyclin B2 (CCNB2)
kl294Hu01 細胞色素P450家族成員1A2(CYP1A2)多克隆抗體 Polyclonal Antibody to Cytochrome P450 1A2 (CYP1A2)
kl294Ra01 細胞色素P450家族成員1A2(CYP1A2)多克隆抗體 Polyclonal Antibody to Cytochrome P450 1A2 (CYP1A2)
