Cat. Number:

Anti-BNP抗體KL-2207R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Brain natriuretic peptide Anti-BNP抗體(BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement Anti-BNP抗體of BNP in blood provides an objective indicator of congestive heart failure severity

Also known as:

BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptideAnti-BNP抗體 precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; ANFB_MOUSE.

Specificity:

Storage:

Shipped at 4℃, Store Anti-BNP抗體at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.