產品詳情
簡單介紹：
Anti-phospho-CDKN2A (Ser140)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-CDKN2A (Ser140)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CDKN2A (Ser140)
Cat. Number:
Anti-phospho-CDKN2A (Ser140)抗體KL-5253R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoformsAnti-phospho-CDKN2A (Ser140)抗體 known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. [provided by RefSeq, Sep 2012].
Also known as:
p-CDKN2A/p16-INK4a(Ser140); p-p16-INK4a(Ser140); cyclin-dependent kinase inhibitor 2A;CDK4I; p16-INK4; p16-INK4a; cyclin-dependent Anti-phospho-CDKN2A (Ser140)抗體kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A, isoform 1; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cell cycle inhibitor; cyclin-dependent kinase inhibitor 2a p16Ink4a; cell cycle regulator; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 2; Cdkn2a; Arf; INK4A; MTS1; p16; p16Cdkn2a; p19ARF; CD2A1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDKN2A around the phosphorylation site of Ser140 [RG(p-S)NH].
●
Predicted Molecular Weight: 17kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-phospho-CDKN2A (Ser140)抗體 (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must beAnti-phospho-CDKN2A (Ser140)抗體 determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must beAnti-phospho-CDKN2A (Ser140)抗體 determined by the end user.
kl992Hu01 Toll樣受體10(TLR10)多克隆抗體 Polyclonal Antibody to Toll Like Receptor 10 (TLR10)
kl994Hu01 抑制蛋白β2(ARRβ2)多克隆抗體 Polyclonal Antibody to Arrestin Beta 2 (ARRb2)
kl995Hu01 血幼素(HJV)多克隆抗體 Polyclonal Antibody to Hemojuvelin (HJV)
kl995Mu01 血幼素(HJV)多克隆抗體 Polyclonal Antibody to Hemojuvelin (HJV)
kl995Ra01 血幼素(HJV)多克隆抗體 Polyclonal Antibody to Hemojuvelin (HJV)
kl996Hu01 載脂蛋白C2(APOC2)多克隆抗體 Polyclonal Antibody to Apolipoprotein C2 (APOC2)
kl996Ra01 載脂蛋白C2(APOC2)多克隆抗體 Polyclonal Antibody to Apolipoprotein C2 (APOC2)
kl997Hu01 載脂蛋白A5(APOA5)多克隆抗體 Polyclonal Antibody to Apolipoprotein A5 (APOA5)
kl998Hu01 KSP鈣黏蛋白(CDH16)多克隆抗體 Polyclonal Antibody to Cadherin 16 (CDH16)
kl999Hu01 基質金屬蛋白酶28(MMP28)多克隆抗體 Polyclonal Antibody to Matrix Metalloproteinase 28 (MMP28)
kl000Hu01 觸珠蛋白相關蛋白(HPR)多克隆抗體 Polyclonal Antibody to Haptoglobin Related Protein (HPR)
kl002Hu01 肝腸鈣黏蛋白(CDH17)多克隆抗體 Polyclonal Antibody to Cadherin 17 (CDH17)
kl003Po01 載脂蛋白B(APOB)多克隆抗體 Polyclonal Antibody to Apolipoprotein B (APOB)
kl005Hu01 大型中性氨基酸轉運蛋白1(LAT1)多克隆抗體 Polyclonal Antibody to Large Neutral Amino Acid Transporter 1 (LAT1)
kl006Ra01 白介素8受體β(IL8Rβ)多克隆抗體 Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb)
kl007Hu01 白介素34(IL34)多克隆抗體 Polyclonal Antibody to Interleukin 34 (IL34)
kl007Mu01 白介素34(IL34)多克隆抗體 Polyclonal Antibody to Interleukin 34 (IL34)
kl009Hu01 S100鈣結合蛋白A2(S100A2)多克隆抗體 Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2)
kl010Hu01 蛋白Z依賴性蛋白酶抑制因子(ZPI)多克隆抗體 Polyclonal Antibody to Protein Z Dependent Protease Inhibitor (ZPI)
kl010Mu01 蛋白Z依賴性蛋白酶抑制因子(ZPI)多克隆抗體 Polyclonal Antibody to Protein Z Dependent Protease Inhibitor (ZPI)
